| Alianza  | |
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| Árabe Unido  | |
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| Atlético Chiriquí  | |
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| | | Founded: 2002 Nickname: Los Purasangre Stadium: Estadio San Cristobal Stadium Address: San Cristobal, David League: Liga Panameña de Fútbol 
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| Chepo  | |
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| | | Founded: 2000 Nickname: Los Naranjas Stadium: Estadio Rommel Fernandez Stadium Address: Avenida José Arango, Panama City League: Liga Panameña de Fútbol
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| Chorrillo  | |
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| Independiente F.C.  | |
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| | | Founded: 1982 Nickname: Los Hijos del Sol Stadium: Estadio Agustín Sánchez Stadium Address: La Chorrera League: Liga Panameña de Fútbol
History: Formerly known as Club Atlético Independiente de la Chorrera or CAI, the club changed names in 2009 after changing owners.
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| Plaza Amador  | |
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| San Francisco  | |
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| Sporting San Miguelito  | |
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| | | Founded: 1989 Nickname: La Academia Stadium: Estadio Rommel Fernandez Stadium Address: Avenida José Arango, Panama City League: Liga Panameña de Fútbol
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| Tauro  | |
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