| Alianza | |
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| Árabe Unido | |
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| Atlético Chiriquí | |
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| | | Founded: 2002 Nickname: Los Purasangre Stadium: Estadio San Cristobal Stadium Address: San Cristobal, David League: Liga Panameña de Fútbol
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| Chepo | |
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| | | Founded: 2000 Nickname: Los Naranjas Stadium: Estadio Rommel Fernandez Stadium Address: Avenida José Arango, Panama City League: Liga Panameña de Fútbol
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| Chorrillo | |
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| Independiente F.C. | |
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| | | Founded: 1982 Nickname: Los Hijos del Sol Stadium: Estadio Agustín Sánchez Stadium Address: La Chorrera League: Liga Panameña de Fútbol
History: Formerly known as Club Atlético Independiente de la Chorrera or CAI, the club changed names in 2009 after changing owners.
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| Plaza Amador | |
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| San Francisco | |
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| Sporting San Miguelito | |
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| | | Founded: 1989 Nickname: La Academia Stadium: Estadio Rommel Fernandez Stadium Address: Avenida José Arango, Panama City League: Liga Panameña de Fútbol
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| Tauro | |
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